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Full-time
Lisbon Metropolitan Area (On-site)
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Senior Researcher Biotechnology – Age Related Disorders

The Senior Researcher will drive experimental research on cellular senescence, immune modulation and aging-related pathways. This role is hands-on in the laboratory, contributing directly to the scientific foundation of Valvian’s longevity pipeline and supporting early therapeutic programs.

Key Responsabilities

  1. Experimental research
  • Design and execute in vitro experiments related to senescence, inflammaging, immune function and metabolic stress.
  • Perform assays such as flow cytometry, cytokine profiling, phenotypic screening, transcriptomics sample prep and senescence markers.
  • Analyse and interpret experimental data and provide clear documentation.
  1. Target and biomarker exploration
  • Investigate pathways associated with aging and age-related immune dysfunction.
  • Support the identification and validation of targets relevant to senescence clearance, immune rejuvenation and metabolic regulation.
  1. Collaboration with AI and multi-omics
  • Provide curated biological data to the AI team.
  • Test experimentally the biological hypotheses and predictions generated by computational models.
  • Contribute to integrated analyses combining omics datasets (transcriptomics, proteomics, glycomics).
  1. Support for preclinical program development
  • Assist in generating data packages for internal decision points and external partners.
  • Conduct preliminary efficacy and mechanism-of-action studies.
  • Prepare material for presentations, internal reviews and investors when needed.
  1. Laboratory operations
  • Ensure proper documentation, reproducibility and adherence to good laboratory practices.
  • Help maintain equipment, reagents and lab workflows in coordination with the lab manager.
  • Mentor junior researchers or interns when appropriate.

Required Qualifications

  • PhD in Cell Biology, Immunology, Biotechnology, Gerontology, Molecular Biology or related fields.

Preferred Experience

  • 3 to 7 years of research experience in areas such as aging biology, senescence, chronic inflammation, immune cell biology or metabolic stress.
  • Strong track record of hands-on lab work and experimental design.
  • Experience with multi-omics or computational biology is a plus, but not required.
  • Previous biotech experience is appreciated but not mandatory.

Soft Skills

  • Excellent wet-lab experimental skills.
  • Ability to analyse complex datasets and derive biological insights.
  • Strong scientific writing skills.
  • Proactive, organised and execution-oriented.
  • Comfortable working in a fast-paced biotech environment.

What We Offer

  • Opportunity to join a high-growth biotech shaping the future of healthy aging.
  • Exposure to cutting-edge science combining wet lab, glycobiology and AI.
  • Direct contribution to early discovery and preclinical programs.
  • Collaboration with international centres and senior scientists.